Dynamics of

Circadian Oscillation

in the SCN

Edited by
Ken-ichi Honma






Aschoff and Honma Prize Winner’s Lecture

Signaling within the Mammalian Circadian Timing System

Ueli Schibler

Part I. Cellular Networks in the Suprachiasmatic Nucleus

Cellular Circadian Rhythms in the Suprachiasmatic Nucleus: An Oscillatory or a Stochastic Process?

Daisuke Ono, Hiroshi Kori, Sato Honma, Serge Daan and Ken-ichi Honma

Imaging Circadian Calcium Rhythm in the Suprachiasmatic Nucleus

Ryosuke Enoki, Sato Honma and Ken-ichi Honma

Mechanism and Modeling of Circadian Phase Wave in the Mammalian Circadian Center

Yasufumi Shigeyoshi, Takeshi Asakawa, Koh-hei Masumoto, Satoshi Koinuma and Mamoru Nagano

Part II. Circadian Pacemaker in the SCN and Behavior Outputs

Circadian Pacemaker for Behavioral Rhythms beyond the SCN

Wataru Nakamura

Cellular Oscillators in the Suprachiasmatic Nucleus for Behavior Rhythm Expression in the Mouse Lacking CRYPTOCHROME

Sato Honma, Daisuke Ono and Ken-ichi Honma

Bout Oscillators: Hypothetical Circadian Oscillators for Activity Bouts

Ken-ichi Honma, Daisuke Ono, Sato Honma and Isao T. Tokuda

Part III. Dynamics of Circadian Oscillation and Oscillatory Networks

Modeling of Feedback Mechanisms in the Suprachiasmatic Nucleus

Mitsuyuki Nakao, Masataka Suzuki, Hiroshi Okayama, Akihiro Karashima and Norihiro Katayama

Phase Oscillator Model as a Tool to Understand Multi-oscillator Dynamics

Hiroshi Kori

Oscillator Network Modeling of the Suprachiasmatic Nucleus in Cry1/Cry2 Double Deficient Mice

Isao T. Tokuda, Hanspeter Herzel, Daisuke Ono, Sato Honma and Ken-ichi Honma

A Reconsideration of Loss of Circadian Rhythms under Low Temperature Conditions

Hiroshi Ito

The Suprachiasmatic Nucleus as a Network of Coupled Oscillators: Adaptation by Learning   

Grigory Bordyugov and Hanspeter Herzel


From Preface

In 2010, after my retirement from full professorship at Hokkaido University, I proposed to several scientists in my research field to have a regular meeting for discussing the circadian biology, especially the functions of the SCN, from a view point of mathematical modeling. ….  The main target of this discussion group is the functional structure of the SCN circadian pacemaker and its relationship with overt rhythms, especially in behavior. …